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Japanese Society for Palliative Medicine
News Letter No.80
日本緩和医療学会ニューズレター
Aug 2018  80
Journal Watch
緩和ケアに関する論文レビュー
名古屋大学大学院医学系研究科 看護学専攻基礎・臨床看護学講座  佐藤 一樹
対象雑誌:N Engl J Med, Lancet, Lancet Oncol, JAMA, JAMA Intern Med, JAMA Oncol, BMJ, Ann Intern Med, J Clin Oncol, Ann Oncol, Eur J Cancer, Br J Cancer, Cancer

対象期間:2018年3月〜5月刊行分

いわゆる“トップジャーナル”に掲載された緩和ケアに関する最新論文を広く紹介します。


【N Engl J Med. 2018;378(9-22)】
1.等張電解質輸液と生理食塩水の非重症救急患者のクラスターRCT(SALT-ED試験)
Self WH, Semler MW, Wanderer JP, Wang L, Byrne DW, Collins SP, Slovis CM, Lindsell CJ, Ehrenfeld JM, Siew ED, Shaw AD, Bernard GR, Rice TW, Investigators S-E. Balanced Crystalloids versus Saline in Noncritically Ill Adults. N Engl J Med. 2018;378(9):819-28. [PMID: 29485926]
2.等張電解質輸液と生理食塩水の重症救急患者のクラスターRCT(SMART試験)
Semler MW, Self WH, Wanderer JP, Ehrenfeld JM, Wang L, Byrne DW, Stollings JL, Kumar AB, Hughes CG, Hernandez A, Guillamondegui OD, May AK, Weavind L, Casey JD, Siew ED, Shaw AD, Bernard GR, Rice TW, Investigators S, the Pragmatic Critical Care Research G. Balanced Crystalloids versus Saline in Critically Ill Adults. N Engl J Med. 2018;378(9):829-39. [PMID: 29485925]
3.癌性胸水に対する留置胸腔カテーテルを用いた外来タルク投与のRCT
Bhatnagar R, Keenan EK, Morley AJ, Kahan BC, Stanton AE, Haris M, Harrison RN, Mustafa RA, Bishop LJ, Ahmed L, West A, Holme J, Evison M, Munavvar M, Sivasothy P, Herre J, Cooper D, Roberts M, Guhan A, Hooper C, Walters J, Saba TS, Chakrabarti B, Gunatilake S, Psallidas I, Walker SP, Bibby AC, Smith S, Stadon LJ, Zahan-Evans NJ, Lee YCG, Harvey JE, Rahman NM, Miller RF, Maskell NA. Outpatient Talc Administration by Indwelling Pleural Catheter for Malignant Effusion. N Engl J Med. 2018;378(14):1313-22. [PMID: 29617585]


【Lancet. 2017; 2018;391(10123-10135)】
4.71カ国の2000〜2014年のがんの予後(CONCORD-3)

Allemani C, Matsuda T, Di Carlo V, Harewood R, Matz M, Niksic M, Bonaventure A, Valkov M, Johnson CJ, Esteve J, Ogunbiyi OJ, Azevedo ESG, Chen WQ, Eser S, Engholm G, Stiller CA, Monnereau A, Woods RR, Visser O, Lim GH, Aitken J, Weir HK, Coleman MP, Group CW. Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries. Lancet. 2018;391(10125):1023-75. [PMID: 29395269]
5.大うつ病の急性期治療での抗うつ薬21医薬品の効果と有害事象のシステマティックレビュー
Cipriani A, Furukawa TA, Salanti G, Chaimani A, Atkinson LZ, Ogawa Y, Leucht S, Ruhe HG, Turner EH, Higgins JPT, Egger M, Takeshima N, Hayasaka Y, Imai H, Shinohara K, Tajika A, Ioannidis JPA, Geddes JR. Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: a systematic review and network meta-analysis. Lancet. 2018;391(10128):1357-66. [PMID: 29477251]
6.電子カルテを用いた高齢者の急性期入院中のフレイル予測スコア
Gilbert T, Neuburger J, Kraindler J, Keeble E, Smith P, Ariti C, Arora S, Street A, Parker S, Roberts HC, Bardsley M, Conroy S. Development and validation of a Hospital Frailty Risk Score focusing on older people in acute care settings using electronic hospital records: an observational study. Lancet. 2018;391(10132):1775-82. [PMID: 29706364]


【Lancet Oncol. 2018;19(3-5)】
7.ベルギーでの進行がんに対する早期緩和ケアのRCT

Vanbutsele G, Pardon K, Van Belle S, Surmont V, De Laat M, Colman R, Eecloo K, Cocquyt V, Geboes K, Deliens L. Effect of early and systematic integration of palliative care in patients with advanced cancer: a randomised controlled trial. Lancet Oncol. 2018;19(3):394-404. [PMID: 29402701]


【JAMA. 2018;319(9-20)】
8.慢性痛に関連する機能障害に対するオピオイドと非オピオイドのRCT
Krebs EE, Gravely A, Nugent S, Jensen AC, DeRonne B, Goldsmith ES, Kroenke K, Bair MJ, Noorbaloochi S. Effect of Opioid vs Nonopioid Medications on Pain-Related Function in Patients With Chronic Back Pain or Hip or Knee Osteoarthritis Pain: The SPACE Randomized Clinical Trial. JAMA. 2018;319(9):872-82. [PMID: 29509867]
9.薬物依存や傷害による死亡率の米国の1980〜2014年の推移と地域差
Dwyer-Lindgren L, Bertozzi-Villa A, Stubbs RW, Morozoff C, Shirude S, Unutzer J, Naghavi M, Mokdad AH, Murray CJL. Trends and Patterns of Geographic Variation in Mortality From Substance Use Disorders and Intentional Injuries Among US Counties, 1980-2014. JAMA. 2018;319(10):1013-23. [PMID: 29536097]
10.薬物過剰摂取死亡でのオピオイド:米国の2010〜2016年の変化(Letter)
Jones CM, Einstein EB, Compton WM. Changes in Synthetic Opioid Involvement in Drug Overdose Deaths in the United States, 2010-2016. JAMA. 2018;319(17):1819-21. [PMID: 29715347]


【JAMA Intern Med. 2018;178(3-5)】
11.カリフォルニア州終末期選択法施行後1年での医師の自殺ほう助の実態(Letter)
Nguyen HQ, Gelman EJ, Bush TA, Lee JS, Kanter MH. Characterizing Kaiser Permanente Southern California’s Experience With the California End of Life Option Act in the First Year of Implementation. JAMA Intern Med. 2018;178(3):417-21. [PMID: 29279895]
12.米国での医療用大麻の合法化とオピオイド処方の関連
Bradford AC, Bradford WD, Abraham A, Bagwell Adams G. Association Between US State Medical Cannabis Laws and Opioid Prescribing in the Medicare Part D Population. JAMA Intern Med. 2018;178(5):667-72. [PMID: 29610897]
13.米国での嗜好用大麻の合法化とオピオイド処方の関連
Wen H, Hockenberry JM. Association of Medical and Adult-Use Marijuana Laws With Opioid Prescribing for Medicaid Enrollees. JAMA Intern Med. 2018;178(5):673-9. [PMID: 29610827]
14.慢性痛での外来オピオイド減量法(letter)
Darnall BD, Ziadni MS, Stieg RL, Mackey IG, Kao MC, Flood P. Patient-Centered Prescription Opioid Tapering in Community Outpatients With Chronic Pain. JAMA Intern Med. 2018;178(5):707-8. [PMID: 29459978]
15.チャプレンによるACPの推進(Letter)
Lee AC, McGinness CE, Levine S, O’Mahony S, Fitchett G. Using Chaplains to Facilitate Advance Care Planning in Medical Practice. JAMA Intern Med. 2018;178(5):708-10. [PMID: 29340565]


【JAMA Oncol. 2018;4(3-5)】
16.がん患者が閲覧可能なオンライン電子カルテの利用状況(Letter)
Pho K, Lu R, Gates S, Xie Y, Lee SJC, Gerber DE. Characteristics of Patients Using Patient Portals in Oncology. JAMA Oncol. 2018;4(3):416-8. [PMID: 29372242]
17.血小板減少法または血液がんでの血小板輸血による止血効果:病原因子低減技術のRCT
Garban F, Guyard A, Labussiere H, Bulabois CE, Marchand T, Mounier C, Caillot D, Bay JO, Coiteux V, Schmidt-Tanguy A, Le Niger C, Robin C, Ladaique P, Lapusan S, Deconinck E, Rolland C, Foote AM, Francois A, Jacquot C, Tardivel R, Tiberghien P, Bosson JL, Evaluation of the Efficacy of Platelets Treated With Pathogen Reduction Process Study G. Comparison of the Hemostatic Efficacy of Pathogen-Reduced Platelets vs Untreated Platelets in Patients With Thrombocytopenia and Malignant Hematologic Diseases: A Randomized Clinical Trial. JAMA Oncol. 2018;4(4):468-75. [PMID: 29392283]
18.神経膠芽腫に対するTTフィールド(電場腫瘍治療)のQOLへの影響
Taphoorn MJB, Dirven L, Kanner AA, Lavy-Shahaf G, Weinberg U, Taillibert S, Toms SA, Honnorat J, Chen TC, Sroubek J, David C, Idbaih A, Easaw JC, Kim CY, Bruna J, Hottinger AF, Kew Y, Roth P, Desai R, Villano JL, Kirson ED, Ram Z, Stupp R. Influence of Treatment With Tumor-Treating Fields on Health-Related Quality of Life of Patients With Newly Diagnosed Glioblastoma: A Secondary Analysis of a Randomized Clinical Trial. JAMA Oncol. 2018;4(4):495-504. [PMID: 29392280]
19.小児がんサバイバーでの医療保険保持のため離職できない問題(短報)
Kirchhoff AC, Nipp R, Warner EL, Kuhlthau K, Leisenring WM, Donelan K, Rabin J, Perez GK, Oeffinger KC, Nathan PC, Robison LL, Armstrong GT, Park ER. “Job Lock” Among Long-term Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. JAMA Oncol. 2018;4(5):707-11. [PMID: 29049517]
20.高齢血液がんサバイバーの認知機能障害と予後
Hshieh TT, Jung WF, Grande LJ, Chen J, Stone RM, Soiffer RJ, Driver JA, Abel GA. Prevalence of Cognitive Impairment and Association With Survival Among Older Patients With Hematologic Cancers. JAMA Oncol. 2018;4(5):686-93. [PMID: 29494732]


【BMJ 2018;360(8143-8154)】
21.米国の医師の支持政党と提供する終末期ケアの関連
Jena AB, Olenski AR, Khullar D, Bonica A, Rosenthal H. Physicians’ political preferences and the delivery of end of life care in the United States: retrospective observational study. BMJ. 2018;361:k1161. [PMID: 29643089]


【Ann Intern Med. 2018;168(5-10)】
22.緩和ケアの総説
Swetz KM, Kamal AH. Palliative Care. Ann Intern Med. 2018;168(5):ITC33-ITC48. [PMID: 29507970]
23.オピオイド鎮痛薬の使用と肺炎リスク
Wiese AD, Griffin MR, Schaffner W, Stein CM, Greevy RA, Mitchel EF, Jr., Grijalva CG. Opioid Analgesic Use and Risk for Invasive Pneumococcal Diseases: A Nested Case-Control Study. Ann Intern Med. 2018;168(6):396-404. [PMID: 29435555]
24.米国の薬物過剰摂取による死亡の人種別の2000年〜2015年の傾向(Letter)
Shiels MS, Freedman ND, Thomas D, Berrington de Gonzalez A. Trends in U.S. Drug Overdose Deaths in Non-Hispanic Black, Hispanic, and Non-Hispanic White Persons, 2000-2015. Ann Intern Med. 2018;168(6):453-5. [PMID: 29204603]
25.低所得患者の慢性疼痛に対する認知行動療法と教育の無作為化比較試験
Thorn BE, Eyer JC, Van Dyke BP, Torres CA, Burns JW, Kim M, Newman AK, Campbell LC, Anderson B, Block PR, Bobrow BJ, Brooks R, Burton TT, Cheavens JS, DeMonte CM, DeMonte WD, Edwards CS, Jeong M, Mulla MM, Penn T, Smith LJ, Tucker DH. Literacy-Adapted Cognitive Behavioral Therapy Versus Education for Chronic Pain at Low-Income Clinics: A Randomized Controlled Trial. Ann Intern Med. 2018;168(7):471-80. [PMID: 29482213]
26.慢性疼痛での医療用大麻の効果(Letter)
Nugent SM, Kansagara D. The Effects of Cannabis Among Adults With Chronic Pain. Ann Intern Med. 2018;168(7):525. [PMID: 29610910]
27.人工呼吸管理中のオピオイド使用と胸壁硬直の関連に関する事例報告(Letter)
Roan JP, Bajaj N, Davis FA, Kandinata N. Opioids and Chest Wall Rigidity During Mechanical Ventilation. Ann Intern Med. 2018;168(9):678. [PMID: 29310135]
28.薬物過剰摂取の拡がりと死体臓器移植ドナー:米国の疫学調査
Durand CM, Bowring MG, Thomas AG, Kucirka LM, Massie AB, Cameron A, Desai NM, Sulkowski M, Segev DL. The Drug Overdose Epidemic and Deceased-Donor Transplantation in the United States: A National Registry Study. Ann Intern Med. 2018;168(10):702-11. [PMID: 29710288]
29.死亡前の急性期治療後施設利用とホスピス利用(Letter)
Lage DE, Caudry DJ, Ackerly DC, Keating NL, Grabowski DC. The Care Continuum for Hospitalized Medicare Beneficiaries Near Death. Ann Intern Med. 2018;168(10):748-50. [PMID: 29435586]


【J Clin Oncol. 2018;36(7-15)】
30.小児緩和ケアチーム介入の関連要因と終末期ケアへの影響
Widger K, Sutradhar R, Rapoport A, Vadeboncoeur C, Zelcer S, Kassam A, Nelson K, Liu Y, Wolfe J, Earle CC, Pole JD, Gupta S. Predictors of Specialized Pediatric Palliative Care Involvement and Impact on Patterns of End-of-Life Care in Children With Cancer. J Clin Oncol. 2018;36(8):801-7. [PMID: 29356606]
31.新規がん診断患者対象のWebを用いたストレス管理プログラムSTREAMのRCT
Urech C, Grossert A, Alder J, Scherer S, Handschin B, Kasenda B, Borislavova B, Degen S, Erb J, Faessler A, Gattlen L, Schibli S, Werndli C, Gaab J, Berger T, Zumbrunn T, Hess V. Web-Based Stress Management for Newly Diagnosed Patients With Cancer (STREAM): A Randomized, Wait-List Controlled Intervention Study. J Clin Oncol. 2018;36(8):780-8. [PMID: 29369731]
32.多発性骨髄腫での骨修飾薬のASCOガイドラインの更新
Anderson K, Ismaila N, Flynn PJ, Halabi S, Jagannath S, Ogaily MS, Omel J, Raje N, Roodman GD, Yee GC, Kyle RA. Role of Bone-Modifying Agents in Multiple Myeloma: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2018;36(8):812-8. [PMID: 29341831]
33.高度催吐性化学療法でのデキサメタゾンの予防投与日数のRCT
Ito Y, Tsuda T, Minatogawa H, Kano S, Sakamaki K, Ando M, Tsugawa K, Kojima Y, Furuya N, Matsuzaki K, Fukuda M, Sugae S, Ohta I, Arioka H, Tokuda Y, Narui K, Tsuboya A, Suda T, Morita S, Boku N, Yamanaka T, Nakajima TE. Placebo-Controlled, Double-Blinded Phase III Study Comparing Dexamethasone on Day 1 With Dexamethasone on Days 1 to 3 With Combined Neurokinin-1 Receptor Antagonist and Palonosetron in High-Emetogenic Chemotherapy. J Clin Oncol. 2018;36(10):1000-6. [PMID: 29443652]
34.QOL改善や終末期ケアの変化に影響する早期緩和ケア介入の要素
Hoerger M, Greer JA, Jackson VA, Park ER, Pirl WF, El-Jawahri A, Gallagher ER, Hagan T, Jacobsen J, Perry LM, Temel JS. Defining the Elements of Early Palliative Care That Are Associated With Patient-Reported Outcomes and the Delivery of End-of-Life Care. J Clin Oncol. 2018;36(11):1096-102. [PMID: 29474102]
35.がん診断後12カ月の症状の推移
Bubis LD, Davis L, Mahar A, Barbera L, Li Q, Moody L, Karanicolas P, Sutradhar R, Coburn NG. Symptom Burden in the First Year After Cancer Diagnosis: An Analysis of Patient-Reported Outcomes. J Clin Oncol. 2018;36(11):1103-11. [PMID: 29494259]


【Ann Oncol. 2018;29(3-5)】
36.子宮がん患者の情報ニードと治療の希望
Oskay-Ozcelik G, Alavi S, Richter R, Keller M, Chekerov R, Cecere SC, Cormio G, Joly F, Kurtz JE, du Bois A, Maciejewski M, Jedryka M, Vergote I, Van Nieuwenhuysen E, Casado A, Mendiola C, Achimas-Cadariu P, Vlad C, Reimer D, Zeimet AG, Friedlander M, Sehouli J. Expression III: patients’ expectations and preferences regarding physician-patient relationship and clinical management-results of the international NOGGO/ENGOT-ov4-GCIG study in 1830 ovarian cancer patients from European countries. Ann Oncol. 2018;29(4):910-6. [PMID: 29415128]
37.化学療法中の栄養介入システマティックレビュー
de van der Schueren MAE, Laviano A, Blanchard H, Jourdan M, Arends J, Baracos VE. Systematic review and meta-analysis of the evidence for oral nutritional intervention on nutritional and clinical outcomes during chemo(radio)therapy: current evidence and guidance for design of future trials. Ann Oncol. 2018;29(5):1141-53. [PMID: 29788170]


【Eur J Cancer. 2018;91-95】
38.膵がん入院患者のQOLの関連要因
Deng Y, Tu H, Pierzynski JA, Miller ED, Gu X, Huang M, Chang DW, Ye Y, Hildebrandt MAT, Klein AP, Zhao R, Lippman SM, Wu X. Determinants and prognostic value of quality of life in patients with pancreatic ductal adenocarcinoma. Eur J Cancer. 2018;92:20-32. [PMID: 29413686]
39.患者会による情報提供の実態:欧米の比較
Lawler M, Prue G, Banks I, Law K, Selby P, McVie G, Sullivan R. Mapping the cancer patient information landscape: A comparative analysis of patient groups across Europe and North America. Eur J Cancer. 2018;92:88-95. [PMID: 29428868]
40.東欧でのがん診断の遅れと予後との関連
Minicozzi P, Walsh PM, Sanchez MJ, Trama A, Innos K, Marcos-Gragera R, Dimitrova N, Botta L, Johannesen TB, Rossi S, Sant M, Group E-W. Is low survival for cancer in Eastern Europe due principally to late stage at diagnosis? Eur J Cancer. 2018;93:127-37. [PMID: 29518726]
41.化学療法後のゾレドロン酸による乳がん患者の骨折予防のRCT(AZURE試験)
Wilson C, Bell R, Hinsley S, Marshall H, Brown J, Cameron D, Dodwell D, Coleman R. Adjuvant zoledronic acid reduces fractures in breast cancer patients; an AZURE (BIG 01/04) study. Eur J Cancer. 2018;94:70-8. [PMID: 29544162]


【Br J Cancer. 2018;118(5-10)】
42.乳がん診断後の就労できなかった期間とその要因
Plym A, Bower H, Fredriksson I, Holmberg L, Lambert PC, Lambe M. Loss in working years after a breast cancer diagnosis. Br J Cancer. 2018;118(5):738-43. [PMID: 29360816]
43.ホジキンリンパ腫長期サバイバーの2次発がんと心血管疾患リスク
de Vries S, Schaapveld M, van Nimwegen FA, Jozwiak K, Lugtenburg PJ, Daniels LA, Roesink JM, van der Maazen RWM, Kok WEM, Aleman BMP, van Leeuwen FE. High burden of subsequent malignant neoplasms and cardiovascular disease in long-term Hodgkin lymphoma survivors. Br J Cancer. 2018;118(6):887-95. [PMID: 29381685]
44.がん患者の鼻出血と喀血リスク
Ording AG, Veres K, Farkas DK, Adelborg K, Sorensen HT. Risk of cancer in patients with epistaxis and haemoptysis. Br J Cancer. 2018;118(6):913-9. [PMID: 29462130]
45.高齢がん患者の一次化学療法での有害事象のリスク予測モデル
Kim JW, Lee YG, Hwang IG, Song HS, Koh SJ, Ko YH, Shin SH, Woo IS, Hong S, Kim TY, Kim SY, Nam BH, Kim HJ, Kim HJ, Lee MA, Kwon JH, Hong YS, Bae SH, Koo DH, Kim KI, Kim JH. Predicting cumulative incidence of adverse events in older patients with cancer undergoing first-line palliative chemotherapy: Korean Cancer Study Group (KCSG) multicentre prospective study. Br J Cancer. 2018;118(9):1169-75. [PMID: 29576622]
46.終末期の話し合いのがん部位別の実態:ベルギーでの死亡小票を基にした全国医師調査
Verkissen MN, Houttekier D, Cohen J, Schots R, Chambaere K, Deliens L. End-of-life decision-making across cancer types: results from a nationwide retrospective survey among treating physicians. Br J Cancer. 2018;118(10):1369-76. [PMID: 29593337]
47.進行がんで受ける治療の社会背景による違い:英国での全国調査
Henson KE, Fry A, Lyratzopoulos G, Peake M, Roberts KJ, McPhail S. Sociodemographic variation in the use of chemotherapy and radiotherapy in patients with stage IV lung, oesophageal, stomach and pancreatic cancer: evidence from population-based data in England during 2013-2014. Br J Cancer. 2018. [PMID: 29743552]


【Cancer. 2018;124(5-10)】
48.治療の副作用による悩みの主観的な単項目評価は実際の有害事象を反映するか
Pearman TP, Beaumont JL, Mroczek D, O’Connor M, Cella D. Validity and usefulness of a single-item measure of patient-reported bother from side effects of cancer therapy. Cancer. 2018;124(5):991-7. [PMID: 29131323]
49.AYA世代がん患者の臨床試験参加
Thomas SM, Malvar J, Tran H, Shows J, Freyer DR. A prospective, observational cohort study comparing cancer clinical trial availability and enrollment between early adolescents/young adults and children. Cancer. 2018;124(5):983-90. [PMID: 29149450]
50.頭頚部がんでの抑うつと予後の関連
Zimmaro LA, Sephton SE, Siwik CJ, Phillips KM, Rebholz WN, Kraemer HC, Giese-Davis J, Wilson L, Bumpous JM, Cash ED. Depressive symptoms predict head and neck cancer survival: Examining plausible behavioral and biological pathways. Cancer. 2018;124(5):1053-60. [PMID: 29355901]
51.免疫チェックポイント阻害薬による内分泌機能不全の総説
Barroso-Sousa R, Ott PA, Hodi FS, Kaiser UB, Tolaney SM, Min L. Endocrine dysfunction induced by immune checkpoint inhibitors: Practical recommendations for diagnosis and clinical management. Cancer. 2018;124(6):1111-21. [PMID: 29313945]
52.小児がんでの高催吐性化学療法による悪心・嘔吐に対する指圧バンドのRCT
Dupuis LL, Kelly KM, Krischer JP, Langevin AM, Tamura RN, Xu P, Chen L, Kolb EA, Ullrich NJ, Sahler OJZ, Hendershot E, Stratton A, Sung L, McLean TW. Acupressure bands do not improve chemotherapy-induced nausea control in pediatric patients receiving highly emetogenic chemotherapy: A single-blinded, randomized controlled trial. Cancer. 2018;124(6):1188-96. [PMID: 29266260]
53.米国のがん患者の栄養補助食品使用の推移
Li C, Hansen RA, Chou C, Calderon AI, Qian J. Trends in botanical dietary supplement use among US adults by cancer status: The National Health and Nutrition Examination Survey, 1999 to 2014. Cancer. 2018;124(6):1207-15. [PMID: 29211315]
54.小児がん患者の両親への予後説明の関連要因
Marron JM, Cronin AM, Kang TI, Mack JW. Intended and unintended consequences: Ethics, communication, and prognostic disclosure in pediatric oncology. Cancer. 2018;124(6):1232-41. [PMID: 29278434]
55.患者報告アウトカムを用いた骨髄異形成症候群の予後予測指標の開発
Efficace F, Cottone F, Abel G, Niscola P, Gaidano G, Bonnetain F, Anota A, Caocci G, Cronin A, Fianchi L, Breccia M, Stauder R, Platzbecker U, Palumbo GA, Luppi M, Invernizzi R, Bergamaschi M, Borin L, Di Tucci AA, Zhang H, Sprangers M, Vignetti M, Mandelli F. Patient-reported outcomes enhance the survival prediction of traditional disease risk classifications: An international study in patients with myelodysplastic syndromes. Cancer. 2018;124(6):1251-9. [PMID: 29231969]
56.AYA世代がん患者の二次発がんリスク
Goldfarb M, Rosenberg AS, Li Q, Keegan THM. Impact of latency time on survival for adolescents and young adults with a second primary malignancy. Cancer. 2018;124(6):1260-8. [PMID: 29205296]
57.がん罹患経験による急性心筋梗塞治療と予後の比較
Gong IY, Yan AT, Ko DT, Earle CC, Cheung WY, Peacock S, Hall M, Gale CP, Chan KKW. Temporal changes in treatments and outcomes after acute myocardial infarction among cancer survivors and patients without cancer, 1995 to 2013. Cancer. 2018;124(6):1269-78. [PMID: 29211307]
58.がん罹患経験による疲れやすさと持久運動能力の比較
Gresham G, Dy SM, Zipunnikov V, Browner IS, Studenski SA, Simonsick EM, Ferrucci L, Schrack JA. Fatigability and endurance performance in cancer survivors: Analyses from the Baltimore Longitudinal Study of Aging. Cancer. 2018;124(6):1279-87. [PMID: 29419879]
59.前立腺がん患者の男性ホルモン除去療法と認知機能障害のレビュー
McHugh DJ, Root JC, Nelson CJ, Morris MJ. Androgen-deprivation therapy, dementia, and cognitive dysfunction in men with prostate cancer: How much smoke and how much fire? Cancer. 2018;124(7):1326-34. [PMID: 29338083]
60.小児がん診断後の両親の収入の推移
Hiyoshi A, Montgomery S, Bottai M, Hoven EI. Trajectories of income and social benefits for mothers and fathers of children with cancer: A national cohort study in Sweden. Cancer. 2018;124(7):1492-500. [PMID: 29430634]
61.消化器がん化学療法中の握力測定の実施可能性
Ordan MA, Mazza C, Barbe C, Perrier M, Botsen D, Renard Y, Moreau J, Brasseur M, Tailliere B, Bertin E, Bouche O. Feasibility of systematic handgrip strength testing in digestive cancer patients treated with chemotherapy: The FIGHTDIGO study. Cancer. 2018;124(7):1501-6. [PMID: 29278424]
62.造血幹細胞移植後サバイバーの生活習慣による虚血性心疾患リスク
Leger KJ, Baker KS, Cushing-Haugen KL, Flowers MED, Leisenring WM, Martin PJ, Mendoza JA, Reding KW, Syrjala KL, Lee SJ, Chow EJ. Lifestyle factors and subsequent ischemic heart disease risk after hematopoietic cell transplantation. Cancer. 2018;124(7):1507-15. [PMID: 29315507]
63.小児・AYA世代がんでの妊孕性保護の総説
Burns KC, Hoefgen H, Strine A, Dasgupta R. Fertility preservation options in pediatric and adolescent patients with cancer. Cancer. 2018;124(9):1867-76. [PMID: 29370455]
64.がん罹患と治療・予後の人種による違いの総説
Fang CY, Tseng M. Ethnic density and cancer: A review of the evidence. Cancer. 2018;124(9):1877-903. [PMID: 29411868]
65.がん患者でのElixhauser併存疾患スコアの有用性
Mehta HB, Sura SD, Adhikari D, Andersen CR, Williams SB, Senagore AJ, Kuo YF, Goodwin JS. Adapting the Elixhauser comorbidity index for cancer patients. Cancer. 2018;124(9):2018-25. [PMID: 29390174]
66.早期乳がん患者の治療後2年間の就労状況
Ekenga CC, Perez M, Margenthaler JA, Jeffe DB. Early-stage breast cancer and employment participation after 2 years of follow-up: A comparison with age-matched controls. Cancer. 2018;124(9):2026-35. [PMID: 29437204]
67.小児がんサバイバーの精神疾患の有害事象のリスク
Nathan PC, Nachman A, Sutradhar R, Kurdyak P, Pole JD, Lau C, Gupta S. Adverse mental health outcomes in a population-based cohort of survivors of childhood cancer. Cancer. 2018;124(9):2045-57. [PMID: 29468664]
68.脳転移での全脳照射の総説
Trifiletti DM, Brown PD. The role of whole-brain radiation therapy in patients with cerebral metastases. Cancer. 2018;124(10):2072-4. [PMID: 29603127]
69.肝細胞がん手術後の漢方による長期的な再発予防効果
Zhai XF, Liu XL, Shen F, Fan J, Ling CQ. Traditional herbal medicine prevents postoperative recurrence of small hepatocellular carcinoma: A randomized controlled study. Cancer. 2018;124(10):2161-8. [PMID: 29499082]
70.乳がん患者の年齢による予後の違い
Freedman RA, Keating NL, Lin NU, Winer EP, Vaz-Luis I, Lii J, Exman P, Barry WT. Breast cancer-specific survival by age: Worse outcomes for the oldest patients. Cancer. 2018;124(10):2184-91. [PMID: 29499074]
71.がん治療薬に対する米国市民の認識
Frosch ZAK, Cronin AM, Gagne JJ, Teschke MP, Gray SW, Abel GA. Cancer drug shortages: Awareness and perspectives from a representative sample of the US population. Cancer. 2018;124(10):2205-11. [PMID: 29635808]
72.進行前立腺がん患者に対する過剰な検査の関連要因とそれによる影響
Golan R, Bernstein AN, Gu X, Dinerman BF, Sedrakyan A, Hu JC. Increased resource use in men with metastatic prostate cancer does not result in improved survival or quality of care at the end of life. Cancer. 2018;124(10):2212-9. [PMID: 29579318]
73.AYA世代がん患者のソーシャルネットワーク評価尺度の開発
Huang IC, Jones CM, Brinkman TM, Hudson MM, Srivastava DK, Li Y, Robison LL, Krull KR. Development of the functional social network index for adolescent and young adult cancer survivors. Cancer. 2018;124(10):2220-7. [PMID: 29517807]
74.がん患者のせん妄での鎮静スケールRASSの臨床的に意義のある最小の差
Hui D, Hess K, Dibaj SS, Arthur J, Dev R, Dalal S, Reddy S, Bruera E. The minimal clinically important difference of the Richmond Agitation-Sedation Scale in patients with cancer with agitated delirium. Cancer. 2018;124(10):2246-52. [PMID: 29469951]

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