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Japanese Society for Palliative Medicine
News Letter No.78
日本緩和医療学会ニューズレター
Feb 2018  78
Journal Watch
緩和ケアに関する論文レビュー
名古屋大学大学院 医学系研究科 看護学専攻 基礎・臨床看護学講座  佐藤 一樹
対象雑誌:N Engl J Med, Lancet, Lancet Oncol, JAMA, JAMA Intern Med, BMJ, Ann Intern Med, J Clin Oncol, Ann Oncol, Eur J Cancer, Br J Cancer, Cancer

対象期間:2017年9月〜11月刊行分

いわゆる“トップジャーナル”に掲載された緩和ケアに関する最新論文を広く紹介します。

【N Engl J Med. 2017; 377(10-22)】
1.女性の妊孕性温存の総説
Donnez J, Dolmans MM. Fertility Preservation in Women. N Engl J Med. 2017;377(17):1657-65. PMID 29069558.

【Lancet. 2017; 390(10098-10110)】
2.COPDの症状緩和の総説
Maddocks M, Lovell N, Booth S, Man WD, Higginson IJ. Palliative care and management of troublesome symptoms for people with chronic obstructive pulmonary disease. Lancet. 2017;390(10098):988-1002. PMID 28872031.
3.高齢者のADL の変化:英国の1991年と2011年の大規模調査
Kingston A, Wohland P, Wittenberg R, Robinson L, Brayne C, Matthews FE, et al. Is late-life dependency increasing or not? A comparison of the Cognitive Function and Ageing Studies (CFAS). Lancet. 2017;390(10103):1676-84. PMID 28821408.

【Lancet Oncol. 2017;18(9-11)】
4.アフリカの緩和ケアの総説
Rhee JY, Garralda E, Torrado C, Blanco S, Ayala I, Namisango E, et al. Palliative care in Africa: a scoping review from 2005-16. Lancet Oncol. 2017;18(9):e522-e31. PMID 28884701.
5.アドバンスケアプラニングACPの定義と推奨に関する国際同意
Rietjens JAC, Sudore RL, Connolly M, van Delden JJ, Drickamer MA, Droger M, et al. Definition and recommendations for advance care planning: an international consensus supported by the European Association for Palliative Care. Lancet Oncol. 2017;18(9):e543-e51. PMID 28884703.

【JAMA. 2017; 318(9-20)】
6.オピオイド依存症の米国の平均余命の2000年〜2015年の推移への影響(短報)
Dowell D, Arias E, Kochanek K, Anderson R, Guy GP, Jr., Losby JL, et al. Contribution of Opioid-Involved Poisoning to the Change in Life Expectancy in the United States, 2000-2015. JAMA. 2017;318(11):1065-7. PMID 28975295.
7.慢性呼吸器疾患の死亡:米国の1980年〜2014年の推移y
Dwyer-Lindgren L, Bertozzi-Villa A, Stubbs RW, Morozoff C, Shirude S, Naghavi M, et al. Trends and Patterns of Differences in Chronic Respiratory Disease Mortality Among US Counties, 1980-2014. JAMA. 2017;318(12):1136-49. PMID 28973621.
8.高齢者のせん妄の診断と治療の総説
Oh ES, Fong TG, Hshieh TT, Inouye SK. Delirium in Older Persons: Advances in Diagnosis and Treatment. JAMA. 2017;318(12):1161-74. PMID 28973626.
9.移民の形態と終末期ケアの関連:カナダのオンタリオ州の調査
Yarnell CJ, Fu L, Manuel D, Tanuseputro P, Stukel T, Pinto R, et al. Association Between Immigrant Status and End-of-Life Care in Ontario, Canada. JAMA. 2017;318(15):1479-88. PMID 28973088.
10.女性の失禁の総説
Lukacz ES, Santiago-Lastra Y, Albo ME, Brubaker L. Urinary Incontinence in Women: A Review. JAMA. 2017;318(16):1592-604. PMID 29067433.
11.救急外来での急性疼痛に対する経口オピオイドと非オピオイド鎮痛薬の無作為化比較試験
Chang AK, Bijur PE, Esses D, Barnaby DP, Baer J. Effect of a Single Dose of Oral Opioid and Nonopioid Analgesics on Acute Extremity Pain in the Emergency Department: A Randomized Clinical Trial. JAMA. 2017;318(17):1661-7. PMID 29114833.
12.高齢者の転倒予防の介入試験のメタアナリシス
Tricco AC, Thomas SM, Veroniki AA, Hamid JS, Cogo E, Strifler L, et al. Comparisons of Interventions for Preventing Falls in Older Adults: A Systematic Review and Meta-analysis. JAMA. 2017;318(17):1687-99. PMID 29114830.
13.医療用大麻のオンライン販売での用量表示の正確性(短報)
Bonn-Miller MO, Loflin MJE, Thomas BF, Marcu JP, Hyke T, Vandrey R. Labeling Accuracy of Cannabidiol Extracts Sold Online. JAMA. 2017;318(17):1708-9. PMID 29114823.
14.非代償期腎不全患者の抑うつに対するセルトラリンの無作為化比較試験
Hedayati SS, Gregg LP, Carmody T, Jain N, Toups M, Rush AJ, et al. Effect of Sertraline on Depressive Symptoms in Patients With Chronic Kidney Disease Without Dialysis Dependence: The CAST Randomized Clinical Trial. JAMA. 2017;318(19):1876-90. PMID 29101402.

【JAMA Intern Med. 2017;177(9-11)】
15.ナーシングホームからの入院予防プログラムの無作為化比較試験
Kane RL, Huckfeldt P, Tappen R, Engstrom G, Rojido C, Newman D, et al. Effects of an Intervention to Reduce Hospitalizations From Nursing Homes: A Randomized Implementation Trial of the INTERACT Program. JAMA Intern Med. 2017;177(9):1257-64. PMID 28672291.
16.慢性疼痛での長期オピオイド使用ガイドラインのアドヒアランスとオピオイド誤用に対する効果:クラスター無作為化比較試験
Liebschutz JM, Xuan Z, Shanahan CW, LaRochelle M, Keosaian J, Beers D, et al. Improving Adherence to Long-term Opioid Therapy Guidelines to Reduce Opioid Misuse in Primary Care: A Cluster-Randomized Clinical Trial. JAMA Intern Med. 2017;177(9):1265-72. PMID 28715535.
17.ナーシングホームでの転倒予防の職員教育のクラスター無作為化比較試験
Colon-Emeric CS, Corazzini K, McConnell ES, Pan W, Toles M, Hall R, et al. Effect of Promoting High-Quality Staff Interactions on Fall Prevention in Nursing Homes: A Cluster-Randomized Trial. JAMA Intern Med. 2017;177(11):1634-41. PMID 28973516.

【BMJ 2017 358(8119-8131)】
なし

【Ann Intern Med. 2017; 167(5-10)】
18.オピオイド処方者の誤用と依存の米国での大規模実態調査
Han B, Compton WM, Blanco C, Crane E, Lee J, Jones CM. Prescription Opioid Use, Misuse, and Use Disorders in U.S. Adults: 2015 National Survey on Drug Use and Health. Ann Intern Med. 2017;167(5):293-301. PMID 28761945.
19.成人慢性疼痛患者に対する医療用大麻の効果と有害事象のシステマティックレビュー
Nugent SM, Morasco BJ, O'Neil ME, Freeman M, Low A, Kondo K, et al. The Effects of Cannabis Among Adults With Chronic Pain and an Overview of General Harms: A Systematic Review. Ann Intern Med. 2017;167(5):319-31. PMID 28806817.
20. PTSD 患者に対する植物由来の医療用大麻の効果と有害事象のシステマティックレビュー
O'Neil ME, Nugent SM, Morasco BJ, Freeman M, Low A, Kondo K, et al. Benefits and Harms of Plant-Based Cannabis for Posttraumatic Stress Disorder: A Systematic Review. Ann Intern Med. 2017;167(5):332-40. PMID 28806794.
21.転移のない前立腺がん患者での骨標的治療のシステマティックレビュー
Alibhai SMH, Zukotynski K, Walker-Dilks C, Emmenegger U, Finelli A, Morgan SC, et al. Bone Health and Bone-Targeted Therapies for Nonmetastatic Prostate Cancer: A Systematic Review and Meta-analysis. Ann Intern Med. 2017;167(5):341-50. PMID 28785760.
22.複合性局所疼痛症候群に対する低用量免疫グロブリン静注治療の無作為化比較試験
Goebel A, Bisla J, Carganillo R, Frank B, Gupta R, Kelly J, et al. Low-Dose Intravenous Immunoglobulin Treatment for Long-Standing Complex Regional Pain Syndrome: A Randomized Trial. Ann Intern Med. 2017;167(7):476-83. PMID 28973211.
23.終末期療養場所の希望の実現の要因(短報)
Callender T, Riley J, Broadhurst H, Wiggins N, Shaw A, Archer S, et al. The Determinants of Dying Where We Choose: An Analysis of Coordinate My Care. Ann Intern Med. 2017;167(7):519-21. PMID 28806816.
24.医師による幇助自殺の倫理と法 国内科学会の Position Paper
Snyder Sulmasy L, Mueller PS, Ethics P, Human Rights Committee of the American College of P. Ethics and the Legalization of Physician-Assisted Suicide: An American College of Physicians Position Paper. Ann Intern Med. 2017;167(8):576-8. PMID 28975242.
25.オレゴン州尊厳死法の 20 年間の経験
Hedberg K, New C. Oregon's Death With Dignity Act: 20 Years of Experience to Inform the Debate. Ann Intern Med. 2017;167(8):579-83. PMID 28975232.
26.民間医療保険を利用する非がん患者でのオピオイド処方:米国の 2001 年から 2013 年の推移( Letter )
Poldervaart JM, Reitsma JB, Six J, Veldkamp RF, Hoes AW. Using the HEART Score in Patients With Chest Pain in the Emergency Department. Ann Intern Med. 2017;167(9):688. PMID 29114751.

【J Clin Oncol. 2017;35(25-33)】
27.10代で親と死別した若年遺族の親への終末期ケアへの不信感と長期的な心理的影響
Beernaert K, Kreicbergs U, Furst CJ, Nyberg T, Steineck G, Bylund-Grenklo T. Distrust in the End-of-Life Care Provided to a Parent and Long-Term Negative Outcomes Among Bereaved Adolescents: A Population-Based Survey Study. J Clin Oncol. 2017;35(27):3136-42. PMID 28787258.
28.乳がんサバイバーのかかりつけ医の役割に関する希望
Wallner LP, Li Y, Furgal AKC, Friese CR, Hamilton AS, Ward KC, et al. Patient Preferences for Primary Care Provider Roles in Breast Cancer Survivorship Care. J Clin Oncol. 2017;35(25):2942-8. PMID 28700276.
29.制吐治療ガイドライン:米国臨床腫瘍学会ガイドラインのアップデート
Hesketh PJ, Kris MG, Basch E, Bohlke K, Barbour SY, Clark-Snow RA, et al. Antiemetics: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2017;35(28):3240-61. PMID 28759346.
30.高齢の白血病患者の終末期の積極治療の推移
Wang R, Zeidan AM, Halene S, Xu X, Davidoff AJ, Huntington SF, et al. Health Care Use by Older Adults With Acute Myeloid Leukemia at the End of Life. J Clin Oncol. 2017;35(30):3417-24. PMID 28783450.
31.小児がんサバイバーの経済的負担
Nipp RD, Kirchhoff AC, Fair D, Rabin J, Hyland KA, Kuhlthau K, et al. Financial Burden in Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. J Clin Oncol. 2017;35(30):3474-81. PMID 28817372.
32.患者と主治医のコミュニケーションのガイドライン:米国臨床腫瘍学会コンセンサス・ガイドライン
Gilligan T, Coyle N, Frankel RM, Berry DL, Bohlke K, Epstein RM, et al. Patient-Clinician Communication: American Society of Clinical Oncology Consensus Guideline. J Clin Oncol. 2017;35(31):3618-32. PMID 28892432.
33.高度催吐性化学療法での遅発性悪心・嘔吐の予防に対するサリドマイドの第V相試験
Zhang L, Qu X, Teng Y, Shi J, Yu P, Sun T, et al. Efficacy of Thalidomide in Preventing Delayed Nausea and Vomiting Induced by Highly Emetogenic Chemotherapy: A Randomized, Multicenter, Double-Blind, Placebo-Controlled Phase III Trial (CLOG1302 study). J Clin Oncol. 2017;35(31):3558-65. PMID 28854065.
34.進行がん診断後1年間の入院率と再入院の予測モデル
Whitney RL, Bell JF, Tancredi DJ, Romano PS, Bold RJ, Joseph JG. Hospitalization Rates and Predictors of Rehospitalization Among Individuals With Advanced Cancer in the Year After Diagnosis. J Clin Oncol. 2017;35(31):3610-7. PMID 28850290.
35.造血幹細胞移植後6カ月での精神的苦悩に対する移植治療中の緩和ケア介入の無作為化比較試験
El-Jawahri A, Traeger L, Greer JA, VanDusen H, Fishman SR, LeBlanc TW, et al. Effect of Inpatient Palliative Care During Hematopoietic Stem-Cell Transplant on Psychological Distress 6 Months After Transplant: Results of a Randomized Clinical Trial. J Clin Oncol. 2017;35(32):3714-21. PMID 28926288.
36.白血病患者の教育や所得レベルと転帰の関連
」 Ostgard LSG, Norgaard M, Medeiros BC, Friis LS, Schoellkopf C, Severinsen MT, et al. Effects of Education and Income on Treatment and Outcome in Patients With Acute Myeloid Leukemia in a Tax-Supported Health Care System: A National Population-Based Cohort Study. J Clin Oncol. 2017;35(32):3678-87. PMID 28892433.
37.英国の性的マイノリティの癌リスク
Saunders CL, Meads C, Abel GA, Lyratzopoulos G. Associations Between Sexual Orientation and Overall and Site-Specific Diagnosis of Cancer: Evidence From Two National Patient Surveys in England. J Clin Oncol. 2017;35(32):3654-61. PMID 28945501.

【Ann Oncol. 2017;28(9-11)】
38.欧州臨床腫瘍学会ESMO指定の早期緩和ケアの拠点病院の実態調査
Hui D, Cherny N, Latino N, Strasser F. The 'critical mass' survey of palliative care programme at ESMO designated centres of integrated oncology and palliative care. Ann Oncol. 2017;28(9):2057-66. PMID 28911084.
39.進行期大腸がんの臨床試験でのQOL測定の総説
Bonnetain F, Borg C, Adams RR, Ajani JA, Benson A, Bleiberg H, et al. How health-related quality of life assessment should be used in advanced colorectal cancer clinical trials. Ann Oncol. 2017;28(9):2077-85. PMID 28430862.
40.非ホジキンリンパ腫の初回治療での満たされないニード
Casulo C, Nastoupil L, Fowler NH, Friedberg JW, Flowers CR. Unmet needs in the first-line treatment of follicular lymphoma. Ann Oncol. 2017;28(9):2094-106. PMID 28430865.
41.乳がん補助療法中の持続型G-CSF製剤ペグフィルグラスチムの効果に関する二次分析
Blackwell K, Gascon P, Jones CM, Nixon A, Krendyukov A, Nakov R, et al. Pooled analysis of two randomized, double-blind trials comparing proposed biosimilar LA-EP2006 with reference pegfilgrastim in breast cancer. Ann Oncol. 2017;28(9):2272-7. PMID 28637287.
42.欧州臨床腫瘍学会ESMOの新規治療評価スケールESMO Magnitude of Clinical Benefit Scale (ESMO-MCBS)の改訂
Cherny NI, Dafni U, Bogaerts J, Latino NJ, Pentheroudakis G, Douillard JY, et al. ESMO-Magnitude of Clinical Benefit Scale version 1.1. Ann Oncol. 2017;28(10):2340-66. PMID 28945867.
43.高催吐性化学療法での化学療法誘発性悪心・嘔吐CINVに対するショウガのプラセボ対照無作為化比較試験
Bossi P, Cortinovis D, Fatigoni S, Cossu Rocca M, Fabi A, Seminara P, et al. A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting (CINV) in patients receiving high-dose cisplatin. Ann Oncol. 2017;28(10):2547-51. PMID 28666335.
44.アジア太平洋地域のがんサバイバーの支持療法ニード、QOL、症状
Molassiotis A, Yates P, Li Q, So WKW, Pongthavornkamol K, Pittayapan P, et al. Mapping unmet supportive care needs, quality-of-life perceptions and current symptoms in cancer survivors across the Asia-Pacific region: results from the International STEP Study. Ann Oncol. 2017;28(10):2552-8. PMID 28961835.
45.中国での2013年のがん死亡と生活習慣の関連
Islami F, Chen W, Yu XQ, Lortet-Tieulent J, Zheng R, Flanders WD, et al. Cancer deaths and cases attributable to lifestyle factors and infections in China, 2013. Ann Oncol. 2017;28(10):2567-74. PMID 28961829.
46.パクリタキセルの神経毒性の臨床的・遺伝子予測因子
Park SB, Kwok JB, Asher R, Lee CK, Beale P, Selle F, et al. Clinical and genetic predictors of paclitaxel neurotoxicity based on patient- versus clinician-reported incidence and severity of neurotoxicity in the ICON7 trial. Ann Oncol. 2017;28(11):2733-40. PMID 29117336.

【Eur J Cancer. 2017;83-86】
47.がん臨床試験のQOLデータ分析で用いられた統計手法の質のシステマティックレビュー
Hamel JF, Saulnier P, Pe M, Zikos E, Musoro J, Coens C, et al. A systematic review of the quality of statistical methods employed for analysing quality of life data in cancer randomised controlled trials. Eur J Cancer. 2017;83:166-76. PMID 28738257.
48.欧州でのがん専門医の卒後教育の実態調査
Benstead K, Turhal NS, O'Higgins N, Wyld L, Czarnecka-Operacz M, Gollnick H, et al. Multidisciplinary training of cancer specialists in Europe. Eur J Cancer. 2017;83:1-8. PMID 28704643.
49.リンパ浮腫のあるメラノーマ患者のQOL
Gjorup CA, Groenvold M, Hendel HW, Dahlstroem K, Drzewiecki KT, Klausen TW, et al. Health-related quality of life in melanoma patients: Impact of melanoma-related limb lymphoedema. Eur J Cancer. 2017;85:122-32. PMID 28918186.
50.プロテインキナーゼ阻害剤治療中の味覚障害
van der Werf A, Rovithi M, Langius JAE, de van der Schueren MAE, Verheul HMW. Insight in taste alterations during treatment with protein kinase inhibitors. Eur J Cancer. 2017;86:125-34. PMID 28987769.
51.がん根治手術後の高齢がん患者の認知機能低下
Plas M, Rotteveel E, Izaks GJ, Spikman JM, van der Wal-Huisman H, van Etten B, et al. Cognitive decline after major oncological surgery in the elderly. Eur J Cancer. 2017;86:394-402. PMID 29100194.

【Br J Cancer. 2017; 117(5-10)】
なし

【Cancer. 2017;123(17-22)】
52.血液がんでホスピス利用の少ない理由
Odejide OO, Cronin AM, Earle CC, Tulsky JA, Abel GA. Why are patients with blood cancers more likely to die without hospice? Cancer. 2017;123(17):3377-84. PMID 28542833.
53.小児がん患者の人生で最もストレスな出来事の認識に関する質的研究
Sharp KMH, Lindwall JJ, Willard VW, Long AM, Martin-Elbahesh KM, Phipps S. Cancer as a stressful life event: Perceptions of children with cancer and their peers. Cancer. 2017;123(17):3385-93. PMID 28472536.
54.がん患者の意欲低下と精神障害や自殺企図の関連
Vehling S, Kissane DW, Lo C, Glaesmer H, Hartung TJ, Rodin G, et al. The association of demoralization with mental disorders and suicidal ideation in patients with cancer. Cancer. 2017;123(17):3394-401. PMID 28472548.
55.小児白血病の長期サバイバーの睡眠・倦怠感・炎症反応と認知・行動的アウトカムの関連
Cheung YT, Brinkman TM, Mulrooney DA, Mzayek Y, Liu W, Banerjee P, et al. Impact of sleep, fatigue, and systemic inflammation on neurocognitive and behavioral outcomes in long-term survivors of childhood acute lymphoblastic leukemia. Cancer. 2017;123(17):3410-9. PMID 28452142.
56.乳がん患者の重度の倦怠感に対するインターネットによる認知行動療法の無作為化比較試験
Abrahams HJG, Gielissen MFM, Donders RRT, Goedendorp MM, van der Wouw AJ, Verhagen C, et al. The efficacy of Internet-based cognitive behavioral therapy for severely fatigued survivors of breast cancer compared with care as usual: A randomized controlled trial. Cancer. 2017;123(19):3825-34. PMID 28621820.
57.外来固形がん患者の併存疾患の負担感と症状の関連
Ritchie CS, Zhao F, Patel K, Manola J, Kvale EA, Snyder CF, et al. Association between patients' perception of the comorbidity burden and symptoms in outpatients with common solid tumors. Cancer. 2017;123(19):3835-42. PMID 28608952.
58.がんスクリーニング検査による精神的苦痛のシステマティックレビュー
Chad-Friedman E, Coleman S, Traeger LN, Pirl WF, Goldman R, Atlas SJ, et al. Psychological distress associated with cancer screening: A systematic review. Cancer. 2017;123(20):3882-94. PMID 28833054.
59.新規に乳がんと診断された女性に対する意思決定支援ネットワーク
Wallner LP, Li Y, McLeod MC, Hamilton AS, Ward KC, Veenstra CM, et al. Decision-support networks of women newly diagnosed with breast cancer. Cancer. 2017;123(20):3895-903. PMID 28640360.
60.AYA世代の若年がん患者でのエンパワーメントとQOLの関連
Kaal SEJ, Husson O, van Duivenboden S, Jansen R, Manten-Horst E, Servaes P, et al. Empowerment in adolescents and young adults with cancer: Relationship with health-related quality of life. Cancer. 2017;123(20):4039-47. PMID 28696580.
61.がんサバイバーでの強度の運動療法による心血管疾患予防の無作為化比較試験
Adams SC, DeLorey DS, Davenport MH, Stickland MK, Fairey AS, North S, et al. Effects of high-intensity aerobic interval training on cardiovascular disease risk in testicular cancer survivors: A phase 2 randomized controlled trial. Cancer. 2017;123(20):4057-65. PMID 28708930.
62.臨床での抑うつスクリーニングツールとしての抑うつ評価尺度HADSとPHQ-9の比較
Hartung TJ, Friedrich M, Johansen C, Wittchen HU, Faller H, Koch U, et al. The Hospital Anxiety and Depression Scale (HADS) and the 9-item Patient Health Questionnaire (PHQ-9) as screening instruments for depression in patients with cancer. Cancer. 2017;123(21):4236-43. PMID 28654189.
63.前立腺がん患者の治療後の後悔
Hurwitz LM, Cullen J, Kim DJ, Elsamanoudi S, Hudak J, Colston M, et al. Longitudinal regret after treatment for low- and intermediate-risk prostate cancer. Cancer. 2017;123(21):4252-8. PMID 28678408.
64.長期がんサバイバーの治療関連イベント、フォローアップケア
Frick MA, Vachani CC, Bach C, Hampshire MK, Arnold-Korzeniowski K, Metz JM, et al. Survivorship and the chronic cancer patient: Patterns in treatment-related effects, follow-up care, and use of survivorship care plans. Cancer. 2017;123(21):4268-76. PMID 28654153.
65.がん患者の家族の抑うつと長期的な運動機能低下の関連
Shaffer KM, Kim Y, Carver CS, Cannady RS. Depressive symptoms predict cancer caregivers' physical health decline. Cancer. 2017;123(21):4277-85. PMID 28661573.
66.長期がんサバイバーでのオピオイド処方
Sutradhar R, Lokku A, Barbera L. Cancer survivorship and opioid prescribing rates: A population-based matched cohort study among individuals with and without a history of cancer. Cancer. 2017;123(21):4286-93. PMID 28782114.
67.医師・看護師教育とがん家族介護者の自信と負担感の関連:CanCORS研究
Mollica MA, Litzelman K, Rowland JH, Kent EE. The role of medical/nursing skills training in caregiver confidence and burden: A CanCORS study. Cancer. 2017;123(22):4481-7. PMID 28727147.
68.米国のがん拠点病院での医療用大麻の使用
Pergam SA, Woodfield MC, Lee CM, Cheng GS, Baker KK, Marquis SR, et al. Cannabis use among patients at a comprehensive cancer center in a state with legalized medicinal and recreational use. Cancer. 2017;123(22):4488-97. PMID 28944449.
69.小児がんの長期サバイバーの慢性C型肝炎と認知機能の関連
Studaway A, Ojha RP, Brinkman TM, Zhang N, Baassiri M, Banerjee P, et al. Chronic hepatitis C virus infection and neurocognitive function in adult survivors of childhood cancer. Cancer. 2017;123(22):4498-505. PMID 28743159.

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