Japanese Society for Palliative Medicine
News Letter No.60
日本緩和医療学会ニューズレター
Aug 2013  60
Journal Watch
東北大学大学院 緩和ケア看護学分野  佐藤 一樹
(レビュー担当:宮下 光令、佐藤 一樹、清水 恵)
 
対象雑誌

対象期間:2013年3月〜5月刊行分

いわゆる“トップジャーナル”に掲載された緩和ケアに関する最新論文を広く紹介します。

【N Engl J Med. 2013;368(10-22)】
CPR への家族の同席(Clinical Decisions)

Downar J, Kritek PA. Family presence during cardiac resuscitation. N Engl J Med. 2013;368(11):1060-2.

【Lancet. 2013;381(9868-80)】
なし

【Lancet Oncol. 2013;14(3-6)】
終末期がん患者の呼吸困難に対する非侵襲的人工呼吸(NIV)と酸素療法のRCT

Nava S, Ferrer M, Esquinas A, Scala R, Groff P, Cosentini R, et al. Palliative use of non-invasive ventilation in end-oflife patients with solid tumours: a randomised feasibility trial. Lancet Oncol. 2013;14(3):219-27.

がん患者の悪液質に対するenobosarmの二重盲検無作為化第U相試験
Dobs AS, Boccia RV, Croot CC, Gabrail NY, Dalton JT, Hancock ML, et al. Eff ects of enobosarm on muscle wasting and physical function in patients with cancer: a double-blind, randomised controlled phase 2 trial. Lancet Oncol. 2013;14(4):335-45.

サハラ以南アフリカの緩和ケア(Series)
Harding R, Selman L, Powell RA, Namisango E, Downing J, Merriman A, et al. Research into palliative care in sub-Saharan Africa. Lancet Oncol. 2013;14(4):e183-8.

【JAMA. 2013;309(9-20)】
デュロキセチンの化学療法による末梢神経障害に対するRCT

Smith EM, Pang H, Cirrincione C, Fleishman S, Paskett ED, Ahles T, et al. Eff ect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial. JAMA. 2013;309(13):1359-67.

【JAMA Intern Med. 2013;173(5-10)】
在宅ホスピスを受ける患者の収入や在宅ホスピスケアの状況と死亡場所の関連

Barclay JS, Kuchibhatla M, Tulsky JA, Johnson KS. Association of hospice patients' income and care level with place of death. JAMA Intern Med. 2013;173(6):450-6.

終末期高齢者のACP(事前ケア計画)の希望と実際
Heyland DK, Barwich D, Pichora D, Dodek P, Lamontagne F, You JJ, et al. Failure to engage hospitalized elderly patients and their families in advance care planning. JAMA Intern Med. 2013;173(9):778-87.

【BMJ. 2013;346(7897-909)】
乳がん術後5〜7年での持続する疼痛と知覚障害

Mejdahl MK, Andersen KG, Gartner R, Kroman N, Kehlet H. Persistent pain and sensory disturbances after treatment for breast cancer: six year nationwide follow-up study. BMJ. 2013;346:f1865.

【BMJ Support Palliat Care. 2013;3(1)】
死や終末期に対する英国民の認識に関する系統的レビュー

Cox K, Bird L, Arthur A, Kennedy S, Kumar A, Pollock K, Stanton A, Seymour S. Public attitudes to death and dying in the UK: A review of published literature. BMJ Support Palliat Care. 2013;3(1):37-45.

英国の緩和ケア患者登録制度での「緩和ケア患者」の定義に関するかかりつけ医GPの認識
Mitchell H, Noble S, Finlay I, Nelson A. Defi ning the palliative care patient: its challenges and implications for service deliver. BMJ Support Palliat Care. 2013;3(1):46-52.

“supportive care”の言葉の定義の明確化のための文献レビューと質的研究
Cramp FA, Bennett M. Development of a generic working defi nition of 'supportive care.' BMJ Support Palliat Care.2013;3(1):53-60.

カナダの原住民での緩和ケアに関する認識
Johnston G, Vukic A. Cultural understanding in the provision of supportive and palliative care: perspectives in relation to an indigenous population. BMJ Support Palliat Care. 2013;3(1):61-68.

進行期心不全患者への緩和ケア提供によるアウトカム改善と費用対効果、非無作為化比較試験
Pattenden JF, Mason AR, Lewin RJ. Collaborative palliative care for advanced heart failure: outcomes and costs from the‘ Better Together’ pilot study. BMJ Support Palliat Care. 2013;3(1):69-76.

オーストラリアの脳卒中ケア病棟での専門的緩和ケア紹介の関連要因
Eastman P, McCarthy G, Brand CA, Weir L, Gorelik A, Le B. Who, why and when: stroke care unit patients seen by a palliative care service within a large metropolitan teaching hospital. BMJ Support Palliat Care. 2013;3(1):77-83.

繊維性間質性肺疾患の終末期患者での事前支持と情報ニードに関する患者・介護者・医療者調査
Bajwah S, Koff man J, Higginson IJ, Ross JR, Wells AU, Birring SS, Riley J.‘I wish I knew more ...’ the end-of-life planning and information needs for end-stage fi brotic interstitial lung disease: views of patients, carers and health professionals. BMJ Support Palliat Care. 2013;3(1):84-90.

終末期在宅療養での地域医療者による予測的処方の課題
Faull C, Windridge K, Ockleford E, Hudson M. Anticipatory prescribing in terminal care at home: what challenges do community health professionals encounter? BMJ Support Palliat Care. 2013;3(1):91-97.

オーストラリアでのオピオイドによる便秘に対するメチルナルトレキソン処方の実態調査
Clark K, Rowett D, Robinson M, Currow DC. Uptake of methylnaltrexone in Australian patients with opioid-induced constipation: a review of the number of prescriptions presented in the fi rst 12 months of subsidization. BMJ Support Palliat Care. 2013;3(1):98-102.

【Ann Intern Med. 2013;158(5-10)】
米国の前立腺患者のがん死亡/ その他の原因による死亡と年齢・腫瘍・併存疾患の関連

Daskivich TJ, Fan KH, Koyama T, Albertsen PC, Goodman M, Hamilton AS, Hoffman RM, Stanford JL, Stroup AM, Litwin MS, Penson DF. Eff ect of age, tumor risk, and comorbidity on competing risks for survival in a U.S.population-based cohort of men with prostate cancer. Ann Intern Med. 2013;158(10):709-17.

メサドンによる不整脈の1997年〜2011年での報告の傾向
Kao D, Bucher Bartelson B, Khatri V, Dart R, Mehler PS, Katz D, Krantz MJ. Trends in reporting methadoneassociated cardiac arrhythmia, 1997-2011: an analysis of registry data. Ann Intern Med. 2013;158(10):735-40.

【J Clin Oncol. 2013;31(7-15)】
米国のNational Consensus Project による小児がん緩和ケアガイドラインに関する遺族と小児腫瘍医の評価

Kassam A, Skiadaresis J, Habib S, Alexander S, Wolfe J. Moving toward quality palliative cancer care: parent and clinician perspectives on gaps between what matters and what is accessible. J Clin Oncol. 2013;31(7):910-5.

がん医療での針治療に関する系統的レビュー
Garcia MK, McQuade J, Haddad R, Patel S, Lee R, Yang P, Palmer JL, Cohen L. Systematic review of acupuncture in cancer care: a synthesis of the evidence. J Clin Oncol. 2013;31(7):952-60.

乳がん患者のフォローアップに関するASCOガイドラインの更新
Khatcheressian JL, Hurley P, Bantug E, Esserman LJ, Grunfeld E, Halberg F, Hantel A, Henry NL, Muss HB, Smith TJ, Vogel VG, Wolff AC, Somerfield MR, Davidson NE. Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol. 2013;31(7):961-5.

がんサバイバーと非がん患者での併存疾患のケアの質指標を比較する後ろ向き研究
Snyder CF, Frick KD, Herbert RJ, Blackford AL, Neville BA, Wolff AC, Carducci MA, Earle CC. Quality of care for comorbid conditions during the transition to survivorship: diff erences between cancer survivors and noncancer controls. J Clin Oncol. 2013;31(9):1140-8.

低リスク好中球減少症がん患者での経口抗生剤に関する多施設共同無作為化比較試験
Kern WV, Marchetti O, Drgona L, Akan H, Aoun M, Akova M, de Bock R, Paesmans M, Viscoli C, Calandra T. Oral Antibiotics for Fever in Low-Risk Neutropenic Patients With Cancer: A Double-Blind, Randomized, Multicenter Trial Comparing Single Daily Moxifl oxacin With Twice Daily Ciprofl oxacin Plus Amoxicillin/Clavulanic Acid Combination Therapy--EORTC Infectious Diseases Group Trial XV. J Clin Oncol. 2013;31(9):1149-56.

小児・若年がん女性患者の妊孕性のガイドラインに関する文献的検討
Metzger ML, Meacham LR, Patterson B, Casillas JS, Constine LS, Hijiya N, Kenney LB, Leonard M, Lockart BA, Likes W, Green DM. Female reproductive health after childhood, adolescent, and young adult cancers: guidelines for the assessment and management of female reproductive complications. J Clin Oncol. 2013;31(9):1239-47.

悪液質のある進行がん患者の食欲不振とその他症状に対するメラトニンの有効性を検証するRCT
Del Fabbro E, Dev R, Hui D, Palmer L, Bruera E. Eff ects of melatonin on appetite and other symptoms in patients with advanced cancer and cachexia: a double-blind placebo-controlled trial. J Clin Oncol. 2013;31(10):1271-6.

がんサバイバーの復職プロセスの性別による違い、フランスの大規模調査
Marino P, Luis Sagaon T, Laetitia M, Anne-Gaelle le CS. Sex diff erences in the return-to-work process of cancer survivors 2 years after diagnosis: results from a large French population-based sample. J Clin Oncol. 2013;31(10):1277-84.

リウマチ治療薬JAF阻害剤ruxolitinibの骨髄線維症に関連した症状に対する有効性を検証するRCT
Mesa RA, Gotlib J, Gupta V, Catalano JV, Deininger MW, Shields AL, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH, Hare T, Erickson-Viitanen S, Sun W, Sandor V, Levy RS, Kantarjian HM, Verstovsek S. Eff ect of ruxolitinib therapy on myelofibrosis-related symptoms and other patient-reported outcomes in COMFORT-I: a randomized, double-blind, placebo-controlled trial. J Clin Oncol. 2013;31(10):1285-92.

ASCO臨床ガイドライン:がん患者でのCVカテーテルのケア
Schiff er CA, Mangu PB, Wade JC, Camp-Sorrell D, Cope DG, El-Rayes BF, Gorman M, Ligibel J, Mansfi eld P, Levine M. Central venous catheter care for the patient with cancer: American Society of Clinical Oncology clinical practice guideline. J Clin Oncol. 2013;31(10):1357-70.

ベルギーのがん患者と非がん患者での終末期ケアの意思決定
(延命治療や積極的安楽死など)の2007年と1998年の比較

Pardon K, Chambaere K, Pasman HR, Deschepper R, Rietjens J, Deliens L. Trends in end-of-life decision making in patients with and without cancer. J Clin Oncol. 2013;31(11):1450-7.

QOPIによる米国の腫瘍内科の外来診療の質の評価、2006年〜2010年の推移
Neuss MN, Malin JL, Chan S, Kadlubek PJ, Adams JL, Jacobson JO, Blayney DW, Simone JV. Measuring the improving quality of outpatient care in medical oncology practices in the United States. J Clin Oncol. 2013;31(11):1471-7.

がん患者の筋肉量減少はBMIと独立した予後因子となる
Martin L, Birdsell L, Macdonald N, Reiman T, Clandinin MT, McCargar LJ, Murphy R, Ghosh S, Sawyer MB, Baracos VE. Cancer cachexia in the age of obesity: skeletal muscle depletion is a powerful prognostic factor, independent of body mass index. J Clin Oncol. 2013;31(12):1539-47.

がん専門家によるがん医療の質改善の介入のレビュー
Coory M, White VM, Johnson KS, Hill DJ, Jeff ord M, Harrison S, Winship I, Millar J, Giles GG. Systematic review of quality improvement interventions directed at cancer specialists. J Clin Oncol. 2013;31(12):1583-91.

青年期にある(YA世代の)進行がん患者での患者- 腫瘍医関係、心理社会的QOL、治療アドヒアランスの関連
Trevino KM, Fasciano K, Prigerson HG. Patient-oncologist alliance, psychosocial well-being, and treatment adherence among young adults with advanced cancer. J Clin Oncol. 2013;31(13):1683-9.

【Ann Oncol. 2013;24(3-5)】
なし

【Eur J Cancer. 2013;49(4-8)
欧州でのがん患者のリハビリの指標EUROCHIP-3

Baili P, Hoekstra-Weebers J, Van Hoof E, Bartsch HH, Travado L, Garami M, Di Salvo F, Micheli A, Veerus P. Cancer rehabilitation indicators for Europe. Eur J Cancer. 2013;49(6):1356-64.

マインドフルネス・ストレス低減法による乳がん患者の不安・抑うつ軽減を示したRCT
Wurtzen H, Dalton SO, Elsass P, Sumbundu AD, Steding-Jensen M, Karlsen RV, Andersen KK, Flyger HL, Pedersen AE, Johansen C. Mindfulness signifi cantly reduces self-reported levels of anxiety and depression: results of a randomised controlled trial among 336 Danish women treated for stage I-III breast cancer. Eur J Cancer. 2013;49(6):1365-73.

がん患者の死亡場所の希望に関するかかりつけ医GPの理解、欧州4か国の調査
Ko W, Beccaro M, Miccinesi G, Van Casteren V, Donker GA, Onwuteaka-Philipsen B, Miralles Espi MT, Deliens L, Costantini M, Van den Block L. Awareness of general practitioners concerning cancer patients' preferences for place of death: evidence from four European countries. Eur J Cancer. 2013;49(8):1967-74.

【Br J Cancer. 2013;108(5-10)】
進行がん患者の全般的QOLの関連要因

A MR, Mayo NE, Gagnon B. Independent contributors to overall quality of life in people with advanced cancer. Br J Cancer. 2013;108(9):1790-800.

看取りのパス「リバプール・ケア・パスウェイ」は看取りの時期でのケアの質を改善するか
Mayland CR, Williams EM, Addington-Hall J, Cox TF, Ellershaw JE. Does the 'Liverpool Care Pathway' facilitate an improvement in quality of care for dying cancer patients? Br J Cancer. 2013;108(10):1942-8.

【Cancer. 2013;119(5-10)】
緩和ケア領域の臨床試験での対象の脱落の発生状況、その理由と予測因子

Hui D, Glitza I, Chisholm G, Yennu S, Bruera E. Attrition rates, reasons, and predictive factors in supportive care and palliative oncology clinical trials. Cancer. 2013;119(5):1098-105.

化学療法施行時の予防的制吐薬使用に関するNCCNガイドラインの順守状況、米国テキサス州
Gomez DR, Liao KP, Giordano S, Nguyen H, Smith BD, Elting LS. Adherence to national guidelines for antiemesis prophylaxis in patients undergoing chemotherapy for lung cancer: a population-based study. Cancer. 2013;119(7):1428-36.

CONNECTというがん患者と腫瘍医のコミュニケーション促進ツールに関するRCT
Meropol NJ, Egleston BL, Buzaglo JS, Balshem A, Benson AB, 3rd, Cegala DJ, Cohen RB, Collins M, Diefenbach MA, Miller SM, Fleisher L, Millard JL, Ross EA, Schulman KA, Silver A, Slater E, Solarino N, Sulmasy DP, Trinastic J, Weinfurt KP. A Web-based communication aid for patients with cancer: the CONNECT Study. Cancer.2013;119(7):1437-45.

がん患者の心的苦痛のケアのための医療者のコミュニケーション技術
Chochinov HM, McClement SE, Hack TF, McKeen NA, Rach AM, Gagnon P, Sinclair S, Taylor-Brown J. Health care provider communication: an empirical model of therapeutic eff ectiveness. Cancer. 2013;119(9):1706-13.

つらさの寒暖計を用いた苦痛スクリーニングの妥当性と利用可能性、イタリアの全国調査
Grassi L, Johansen C, Annunziata MA, Capovilla E, Costantini A, Gritti P, Torta R, Bellani M. Screening for distress in cancer patients: a multicenter, nationwide study in Italy. Cancer. 2013;119(9):1714-21.

姉妹が乳がんと診断された女性の苦痛と乳がんリスクの認識
Metcalfe KA, Quan ML, Eisen A, Cil T, Sun P, Narod SA. The impact of having a sister diagnosed with breast cancer on cancer-related distress and breast cancer risk perception. Cancer. 2013;119(9):1722-8.

局所前立腺がんに対する3 種類の放射線照射方法でのQOLの比較
Gray PJ, Paly JJ, Yeap BY, Sanda MG, Sandler HM, Michalski JM, Talcott JA, Coen JJ, Hamstra DA, Shipley WU, Hahn SM, Zietman AL, Bekelman JE, Efstathiou JA. Patient-reported outcomes after 3-dimensional conformal, intensity-modulated, or proton beam radiotherapy for localized prostate cancer. Cancer. 2013;119(9):1729-35.

非小細胞がん患者に対する緩和ケアのオンラインサポートシステムに関するRCT
Gustafson DH, DuBenske LL, Namkoong K, Hawkins R, Chih MY, Atwood AK, Johnson R, Bhattacharya A, Carmack CL, Traynor AM, Campbell TC, Buss MK, Govindan R, Schiller JH, Cleary JF. An eHealth system supporting palliative care for patients with non-small cell lung cancer: a randomized trial. Cancer. 2013;119(9):1744-51.

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