Japanese Society for Palliative Medicine
News Letter No.40
日本緩和医療学会ニューズレター
Aug 2008  40
Journal Watch
聖隷三方原病院 緩和支持治療科  森田達也
対象雑誌

対象期間:2008年4月から2008年6月(到着分まで)

年々緩和ケアについての系統的レビューやRCTが増えています。時間のない方は系統的レビューだけでも各病院やチームの抄読会で読まれることをお勧めします

Reviews, recommendations, meta-analyses, randomized controlled trials, and large surveys
対象雑誌に掲載された医学論文のうち緩和ケアの臨床家にとって有用と思われる、レビュー、学会の推奨、メタアナライシス、無作為化試験、あるいは、大規模サーベイなどを列記します。

悪液質
Tan BHL, Deans DAC, Skipworth RJE, Ross JA, Fearon KCH. Biomarkers for cancer cachexia: is there also a genetic component to cachexia? Support Care Cancer. 2008; 16(3):229-234.

倦怠感
Olso K, Turner AR, Courneya KS, et al. Possible links between behavioral and physiological indices of tiredness, fatigue, and exhaustion in advanced cancer. Support Care Cancer. 2008; 16(3):241-249.

オンタリオの緩和ケアの州レベルでのモニタリングの結果
Barbera L, Paszat L, Qui F. End-of-life care in lung cancer patients in Ontario: aggressiveness of care in the population and a description of hospital admissions. J Pain Symptom Manage. 2008; 35(3):267-274.

突出痛に対するモルヒネの静脈投与
Mercadante S, Intravaia G, Villari P, Ferrera P, Riina S, Mangione S. Intravenous morphine for breakthrough (Episodic-) pain in an acute palliative care unit: a confirmatory study. J Pain Symptom Manage. 2008; 35(3):307-313.

呼吸困難の治療のレビュー
Viola R, Kiteley C, Lloyd NS, et al. The management of dyspnea in cancer patients: a systematic review. Support Care Cancer. 2008; 16(4):329-337.

化学療法中の患者の予後予測:PaPスコア
Tassinari D, Montanari L, Maltoni M, et al. The palliative prognostic score and survival in patients with advanced solid tumors receiving chemotherapy. Support Care Cancer. 2008; 16(4):359-370.

緩和ケアチームの有効性のRCT
Gade G, Venohr I, Connor D, et al. Impact of an inpatient palliative care team: a randomized controlled trial. J Palliat Med. 2008; 11(2):180-190.

モルヒネを呼吸困難に使っても呼吸機能は悪化しない
Clemens KE, Quednau I, Klaschik E. Is there a higher risk of respiratory depression in opioid-naive palliative care patients during symptomatic therapy of dyspnea with strong opioids? J Palliat Med. 2008; 11(2):204-216.

悪液質についての栄養治療のレビュー
Bosaeus I. Nutritional support in multimodal therapy for cancer cachexia. Support Care Cancer. 2008; 16(5):447-451.

リバプールパスウエイの多施設での効果
Veerbeek L, van Zuylen L, Swart SJ, et al. The effect of the Liverpool care pathway for the dying: a multi-centre study. Palliat Med. 2008; 22(2):145-151.

家族の情報ニードのレビュー
Docherty A, Owens A, Asadi-Lari M, Petchey R, Williams J, Carter YH. Knowledge and information needs of informal caregivers in palliative care: a qualitative systematic review. Palliat Med. 2008; 22(2):153-171.

ホットフラッシュに対するリラクゼーションのRCT
Fenlon DR, Corner JL, Haviland JS. A randomized controlled trial of relaxation training to reduce hot flashes in women with primary breast cancer. J Pain Symptom Manage. 2008; 35(4):397-405.

ボツリヌスの疼痛のRCT
Hagen NA, du Souich P, Lapointe B, et al. Tetrodotoxin for moderate to severe cancer pain: a randomized, double blind, parallel design multicenter study. J Pain Symptom Manage. 2008; 35(4):420-429.

皮下輸液:レビュー
Remington R, Hultman T. Hypodermoclysis to treat dehydration: A review of the evidence. J Am Geriatr Soc. 2007; 55:2051-2055.

末梢性オピオイド拮抗薬のRCT
Thomas J, Karver S, Cooney GA, et al. Methylnaltrexone for opioid-induced constipation in advanced illness. N Engl J Med. 2008; 358(22):2332-2343.

From Japan
ディストレスサーモメーターを使って看護師が精神科受診をアシストする
Shimizu K, Akizuki N, Akechi T, et al. Clinical experience of the modified nurse-assisted screening and psychiatric referral program. Palliat Support Care. 2008; 6(1):29-32.

緩和ケア病棟に紹介するときのバリア
Miyashita M, Hirai K, Morita T, Sanjo M, Uchitomi Y. Barriers to referral to inpatient palliative care units in Japan: a qualitative survey with content analysis. Support Care Cancer. 2008; 16(3):217-222.

5つめのバイタルサインとして苦痛を体温版に入れるシステム
Morita T, Fujimoto K, Namba M, et al. Screening for discomfort as the fifth vital sign using an electronic medical recording system: a feasibility study. J Pain Symptom Manage. 2008; 35(4):430-436.

モルヒネからオキシコドンへのローテーション
Narabayashi M, Sanjo Y, Takenoshita S, et al. Opioid rotation from oral morphine to oral oxycodone in cancer patients with intolerable adverse effects: An open-label trial. Jpn J Clin Oncol. 2008; 38(4):296-304.

フェントラミンの鎮痛補助
Yasukawa M, Yasukawa K, Kamiizumi Y, Yokoyama R. Intravenous phentolamine infusion alleviates the pain of abdominal visceral cancer, including pancreatic cancer. J Anesthesiol. 2007; 21:420-423.

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